[Event Preview] MSD Research Seminar Series- “Hydrogen Medicine Materials”

Date: 26th November 2025 (Wednesday)

Time: 15:30 - 16:30

Venue: O603

Theme: MSD Research Seminar Series- “Hydrogen Medicine Materials”

Language: Mandarin

Speaker’s Biography

Dr. Qianjun He earned his PhD in 2010 from Shanghai Institute of Ceramics, Chinese Academy of Sciences, and was then assigned as an Assistant Professor there. He moved to University of Leeds in 2012 to receive a Marie Curie Fellowship. After two years, he joined the Laboratory of Molecular Imaging and Nanomedicine, NIBIB, National Institutes of Health (NIH, USA), as a postdoc. In 2015, he joined Shenzhen University as a Tenured Professor. In 2022, he moved to Shanghai Jiao Tong University (SJTU) and was appointed a Tenured Professor of Materials Science. Currently, he is a Distinguished Professor of School of Materials Science and Engineering at SJTU. His research focuses on the engineering and development of advanced nanomaterials and nanomedicines for precision theranostics and hydrogen therapy of intractable diseases. As the first author or corresponding author, he has published more than 100 peer-reviewed papers (h index of 70) in Sci. Adv., Nat. Commun., Cell Biomater., etc. He is a winner of Distinguished Young Scientists of National Natural Science Foundation of China. He was awarded Distinguished Leadership in Molecular Hydrogen Research by European Academy for Molecular Hydrogen Research in Biomedicine (2022). He currently is the President of International Society for Hydrogen Medicine and Biology. He is sitting the Associate Editors of Medical Gas Research. More detailed information can be found in his homepage: https://www.x-mol.com/groups/he_qianjun?lang=en

Research interests:

Biomedical Materials, Hydrogen Medicine, Nano-Catalytic Medicine, Drug Delivery

Seminar Introduction:

Hydrogen molecules have a wide-spectrum anti-oxidation and anti-inflammation effect, and exhibit a clear biological effects and high biosafety in treatment of many inflammation-related diseases. Hydrogen therapy becomes an emerging and promising therapeutic strategy. However, hydrogen medicine currently faces three major issues, including (1) what is the fundamental principle of hydrogen therapy; (2) how to real-time detect hydrogen molecules in vivo; (3) how to efficiently deliver hydrogen molecules to the focus. We propose to define “Hydrogen Medicine Materials” as a new concept of biomedical materials specifically engineered to overcome critical challenges in hydrogen medicine, including exploration of bioeffects and mechanisms of H2 by in vivo monitoring of H2 transportation, metabolism and transformation, enhancement of H2 therapeutic efficacy against various oxidative stress-related diseases by high-efficiency and site-specific delivery and controlled release of H2, etc. In an attempt to overcome address these challenges, our group does researches about principle exploration, tool development and materials application, harvesting a series of innovative achievements, mainly including: (1) we have discovered the biological target of hydrogen molecules, and revealed the fundamental principles of H2 anti-inflammation, anti-cancer and anti-senescence; (2) we have developed the first bio-probe of H2, and testified high bio-barriers-crossing capability of H2; (3) we have developed a series of novel H2-delivering biomaterials to enhance H2 delivery efficacy and applied these materials for treatment of major intractable diseases. This report will present the related research advances achieved by us in the recent years.

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